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Savant atibax ciprofloxacina 500 mg/kg), which significantly increased the total number and size of the intestinal lesions. lesions produced a significant inflammatory response in both the experimental group and control mice. The lesions in experimental group were comparable to those seen in human IBD. The results demonstrate that this compound reduces the development of IBD, especially in genetically susceptible mice. Citation: Koyuki H, Takahashi T, Miyabiyama Y (2015) A Novel Approach to Treat Crohn Disease Using an Antibiotic, Analgesia and Anti Inflammatory Therapy: A Single Case Report. PLoS ONE 10(4): e0129093. https://doi.org/10.1371/journal.pone.0129093 Editor: Toni H. Domingoz, Hospital del Mar Medical Center, PORTUGAL Received: February 7, 2015; Accepted: March 8, Published: April 5, 2015 Copyright: © Koyuki et al. This is an open access article distributed under the terms of Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited Data Availability: All applicable are within the paper and its Supporting Information files (Table S1). Funding: The authors have no support or funding to repo